Abstract Chickens genetically resistant to avian influenza could prevent future outbreaks.In chickens, influenza A virus (IAV) Nail Scissors relies on host protein ANP32A.Here we use CRISPR/Cas9 to generate homozygous gene edited (GE) chickens containing two ANP32A amino acid substitutions that prevent viral polymerase interaction.After IAV challen

According to the expensive brain hypothesis, periodic energy level determines the brain mass.However, various environmental and biological factors directly or indirectly relevant to energy intake have not been well studied.Here, we systematically Face Masks examined how body mass, hibernation, diurnally, substrate use, diet individually and synergi

A hobbed gear has pitch, profile, and helix deviations caused by various factors.However it is hard for even experts to specify which factors cause individual deviations from the measured ones.Therefore, a hobbing-machine-diagnosis system could play a key role in identifying the factors from hobbed-gear deviations.Artificial intelligence for image

Manual dexterity measures can be Cooking Toys useful for early detection of age-related functional decline and for prediction of cognitive decline.However, what aspects of sensorimotor function to assess remains unclear.Manual dexterity markers should be able to separate impairments related to cognitive decline from those related to healthy aging.I

Lagunamides A (<strong>1</strong>) and B (<strong>2</strong>) are potent cytotoxic cyclic depsipeptides PEPPERMINT isolated from the filamentous marine cyanobacterium, <em>Lyngbya majuscula</em>, from Pulau Hantu, Singapore.These compounds are structurally related to the aurilide-class of molecules, which have be